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Pomalidomide-C2-NH2 hydrochloride

CAS No. 2305369-00-8

Pomalidomide-C2-NH2 hydrochloride( —— )

Catalog No. M24047 CAS No. 2305369-00-8

Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 28 In Stock
5MG 46 In Stock
10MG 71 In Stock
25MG 155 In Stock
50MG 230 In Stock
100MG 340 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Pomalidomide-C2-NH2 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
  • Description
    Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    E3 Ligase Ligand
  • Recptor
    cereblon (CRBN) E3 ligase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2305369-00-8
  • Formula Weight
    352.77
  • Molecular Formula
    C15H17ClN4O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (354.34 mM)
  • SMILES
    O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCN)=O.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shibata N , Nagai K , Morita Y , et al. Development of protein degradation inducers of androgen receptor by conjugation of androgen receptor ligands and inhibitor of apoptosis protein (IAP) ligands[J]. Journal of Medicinal Chemistry, 2017:acs.jmedchem.7b00168.
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